14 century BC: Apaša, the capital of the Asia Minor kingdom of Arzawa was destroyed by the Hittite king, Mursili III.
1047 BC: According to myth, Ephesus was founded
600 BC: Pythagoras became a tyrant, adopted an anti-aristocratic policy and turned the Basilides away.
561 BC: Tyrant Pindar, was exiled by Croesus, the king of Lydia
550 BC: the Athenian Aristarchus established democracy
546 BC: Ephesus was conquered by the Persians
499-498 BC: Ionian Revolt
492 BC: establishment of a democratic regime
466 BC: Ephesus joined the Delian League
412 BC: Ephesus defected from the Delian League
409 BC: failed attempt by the Athenians to capture Ephesus and to extract money
407 BC: Lysander choοse Ephesus as a base for the Spartan expeditionary force
405 BC: Lysander returned to Ephesus
399 BC: Thirbon comes in Ephesus
395 BC: Agesilaus choose Ephesus as a military base for his operations in Asia Minor
394 BC: Ephesus declared for Conon. However the city was under the Spartan control.
387 BC: Peace of Antalcidas, the city returned to the Persians.
c. 370 BC: Autophradates captured Ephesus
336 BC: Parmenion in Asia Minor. Democratic revolt in Ephesus. The oligarchy returned to power soon.
334 BC: Αlexander entered Ephesus. The democratic followers of the Macedonians started to slaughter the oligarchic supporters . Alexander stopped the bloodshed and restored democracy.
324 BC: tyrant Hegesias' assassination
320 BC: Ephesus came briefly under Antigonus
318-302 BC: Ephesus under the control of Antigonus
302 BC: Temporary capture of Ephesus by Prepelaos
301-294 BC: Ephesus under the control of Demetrius the Besieger
300-297 BC: War with Priene. Ephesus went under bankrupt. Abolition of debts..
294 BC: Foundation of Arsinoea (New Ephesus) by settlement of Ephesus, Lebedus, Fygela and Kolophon
281 BC: the city took back its old name and gained its autonomy, althought it was under the Seleucid rule.
264 BC: Ephesus came under the control of the Lagids
261-260 BC: the son and successor of Ptolemy II revolted against his father, but was killed by his mercenaries.
260-253 BC: Second Syrian War. Rhodes entered into an alliance with Antioch II. The city of Ephesos was captured by Antioch II.
246 BC: Ephesus became the seat of the Seleucid garrison and Laodice’s place of residence.
246-241 BC: Third Syrian War. Ephesus came again under the Lagid control until 197 BC..
197 BC: the city was captured by Antioch III΄
188 BC: Ephesus became part of the Attalid Kingdom 134 π.Χ.: After Attalus III will, Ephesus became a free city.
131 BC: the Ephesian fleet won a decisive victory against Aristonicus.
129 BC: Ephesus remained a free city of the province of Asia and became the seat of the proconsul of the province.
104 BC: The legal controversy with the roman tax collectors ended in favour of Ephesus.
88 BC: Mithridates of Ephesus called the Greeks of Asia to slaughter the Romans. 80.000 men died during this turbulent period.
88-87 BC: Ephesus rebelled against Mithridates and sided with Rome.
86 BC: The Roman general Sylla convened a congress in Ephesus and asked to pay high war indemnities.
48 BC: Julius Caesar visited Ephesus
41 BC: Marcus Antonius entered the city as a New Dionysus during a Bacchic ritual
33 BC: Marcus Antonius and Cleopatra wintered in Ephesus. 300 senators with 500 war ships met them there.
29 BC: Augustus spent six months in Ephesus. The city was declared capital of Asia.
23 BC: Devastating earthquake. The city was helped by the imperial house.
53-55 AD: Paul visited Ephesus. Revolt of the goldsmiths.
65 AD: the city was for first time called Neokoros of Artemis
88-89 AD: First Neokoria
113/114 AD: Trajan visited the city
124 AD: Hadrian’s first visit in Ephesus
129/130 AD: Hadrian’s second visit in Ephesus. Second Neocoria
162/163 AD: Emperor Lucius Verus visited Ephesus.
166/167 AD: Lucius Verus returns in Ephesus from the Parthian Expedition.
210/211 AD: Third Neocoria, which was invalidated after Caracalla’s death.
262 AD: Goths’ invasion, after the destruction of the sanctuary of Artemis by an earthquake. The city’s coinage ends and the neokoria vanished.